Scientific Publications

2020

Andrews, E. S. V., & Arcus, V. L. PhoH2 proteins couple RNA helicase and RNAse activities. Protein Science (2020) 29(4): 883-892. 

Andrews, E. S. V., Rzoska-Smith, E., & Arcus, V. L. Post-transcriptional modulation of the SigF regulon in Mycobacterium smegmatis by the PhoH2 toxin-antitoxin. PLoS ONE (2020) 15: e0236551.

Azimi, I., Stevenson, R. J., Zhang, X., Meizoso-Huesca, A., Xin, P., Johnson, M., Flanagan, J. U., Chalmers, S. B., Yoast, R. E., Kapure, J. S., Ross, B. P., Vetter, I., Ashton, M. R., Launikonis, B. S., Denny, W. A., Trebak, M., & Monteith, G. R. A New Selective Pharmacological Enhancer of the Orai1 Ca2+ Channel Reveals Roles for Orai1 in Smooth and Skeletal Muscle Functions. ACS Pharmacology and Translational Science (2020) 3(1): 135-147.

Barad, Z., Khant Aung, Z., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. Impaired prolactin transport into the brain and functional responses to prolactin in aged male mice. Journal of Neuroendocrinology (2020) 32(8): e12889.

Bashiri, G., Nigon, L. V., Jirgis, E. N. M., Ho, N. A. T., Stanborough, T., Dawes, S. S., Baker, E. N., Bulloch, X. E. M. M., &  Johnston, X. J. M. Allosteric regulation of menaquinone (Vitamin K2) biosynthesis in the human pathogen Mycobacterium tuberculosis. Journal of Biological Chemistry (2020) 295(12): 3759-3770. 

Boons, G., Vandamme, T., Ibrahim, J., Roeyen, G., Driessen, A., Peeters, D., Lawrence, B., Print, C., Peeters, M., Van Camp, G., & de Beeck, K. O. PDX1 DNA methylation distinguishes two subtypes of pancreatic neuroendocrine neoplasms with a different prognosis. Cancers (2020) 12(6): 1461.

Bracegirdle, J., Gordon, D. P., Harvey, J. E., & Keyzers, R. A. Kinase-Inhibitory Nucleoside Derivatives from the Pacific Bryozoan Nelliella nelliiformis. Journal of Natural Products (2020) 83(2): 547-551.

Brooks, A. E. S., Iminitoff, M., Williams, E., Damani, T., Jackson-Patel, V., Fan, V., James, J., Dunbar, P. R., Feisst, V. & Sheppard, H. M, Ex Vivo Human Adipose Tissue Derived Mesenchymal Stromal Cells (ASC) Are a Heterogeneous Population That Demonstrate Rapid Culture-Induced Changes. Frontiers in Pharmacology (2020) 10: 1695.

Burn, O. K., Prasit, K. K., & Hermans, I. F. Modulating the tumour microenvironment by intratumoural injection of pattern recognition receptor agonists. Cancers (2020) 12(12): 1-22. 

Busby, B. P., Niktab, E., Roberts, C. A., Sheridan, J. P., Coorey, N. V., Senanayake, D. S., Connor, L. M., Munkacsi, A. B., & Atkinson, P. H. Erratum: Publisher Correction: Genetic interaction networks mediate individual statin drug response in Saccharomyces cerevisiae. NPJ systems biology and applications (2020) 6: 9. 

Calvert, M. B., Furkert, D. P., Cooper, C. B., & Brimble, M. A. Synthetic approaches towards bedaquiline and its derivatives. Bioorganic and Medicinal Chemistry Letters (2020) 30(12): 127172.

Cameron, A. J., Davison, E. K., An, C., Stubbing, L. A., Dunbar, P. R., Harris, P. W. R., & Brimble, M. A. Synthesis and SAR Analysis of Lipovelutibols B and D and Their Lipid Analogues. Journal of Organic Chemistry (2020) 85(3): 1401-1406. 

Cameron, A. J., Harris, P. W. R., & Brimble, M. A. On-Resin Preparation of Allenamidyl Peptides: A Versatile Chemoselective Conjugation and Intramolecular Cyclisation Tool. Angewandte Chemie - International Edition (2020) 59(41): 18054-18061. 

Chung, A. W., Ho, T. K. C., Hanson-Manful, P., Tritscheller, S., Raynes, J. M., Whitcombe, A. L., Tay, M. L., McGregor, R., Lorenz, N., Oliver, J. R., Gurney, J. K., Print, C. G., Wilson, N. J., Martin, W. J., Williamson, D. A., Baker, M. G., & Moreland, N. J.  Systems immunology reveals a linked IgG3–C4 response in patients with acute rheumatic fever. Immunology and Cell Biology (2020) 98(1): 12-21. 

Davison, E. K., Freeman, J. L., Zhang, W., Wuest, W. M., Furkert, D. P., & Brimble, M. A. Asymmetric Total Synthesis of the Naturally Occurring Antibiotic Anthracimycin. Organic Letters (2020) 22(14): 5550-5554. 

Dissanayake, W. C., Sorrenson, B., Lee, K. L., Barre, S., & Shepherd, P. R.  Α-Catenin isoforms are regulated by glucose and involved in regulating insulin secretion in rat clonal β-cell models. Biochemical Journal (2020) 477(4): 763-772.  

Eiholzer, R. A., Mehta, S., Kazantseva, M., Drummond, C. J., McKinney, C., Young, K., Slater, D., Morten, B. C., Avery-Kiejda, K. A., Lasham, A., Fleming, N., Morrin, H. R., Reader, K., Royds, J. A., Landmann, M., Petrich, S., Reddel, R., Huschtscha, L., Taha, A., Hung, N. A., Slatter, T. L., & Braithwaite, A. W.  Intronic TP53 Polymorphisms Are Associated with Increased Δ133TP53 Transcript, Immune Infiltration and Cancer Risk. Cancers (Basel) (2020) 12(9): 2472.

Eom, J., Park, S. M., Feisst, V., Chen, C. J. J., Mathy, J. E., McIntosh, J. D., Angel, C. E., Bartlett, A., Martin, R., Mathy, J. A., Cebon, J. S., Black, M. A., Brooks, A. E. S., & Dunbar, P. R.  Distinctive subpopulations of stromal cells are present in human lymph nodes infiltrated with melanoma. Cancer Immunology Research (2020) 8(8): 990-1003.

Ferrer-Font, L., Mayer, J. U., Old, S., Hermans, I. F., Irish, J., & Price, K. M. High-Dimensional Data Analysis Algorithms Yield Comparable Results for Mass Cytometry and Spectral Flow Cytometry Data. Cytometry Part A (2020) 97(8): 824-831. 

Ferrer-Font, L., Mehta, P., Harmos, P., Schmidt, A. J., Chappell, S., Price, K. M., Hermans, I. F., Ronchese, F., Le Gros, G., & Mayer, J. U. High-dimensional analysis of intestinal immune cells during helminth infection. eLife (2020) 9: e51678.

Freeman, J. L., Li, F. F., Furkert, D. P., & Brimble, M. A.  Synthetic Studies towards Spirocyclic Imine Marine Toxins Using N -Acyl Iminium Ions as Dienophiles in Diels-Alder Reactions. Synlett (2020) 31(7): 657-671. 

Gaar, J., Naffa, R., & Brimble, M. Enzymatic and non-enzymatic crosslinks found in collagen and elastin and their chemical synthesis. Organic Chemistry Frontiers (2020) 7(18): 2789-2814. 

Garelja, M. L., Au, M., Brimble, M. A., Gingell, J. J., Hendrikse, E. R., Lovell, A., Prodan, N., Sexton, P. M., Siow, A., Walker, C. S., Watkins, H. A., Williams, G. M., Wootten, D., Yang, S. H., Harris, P. W. R. & Hay, D. L.  Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors. ACS Pharmacology and Translational Science (2020) 3(2): 246-262. 

Georgescu, T., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. Acute effects of prolactin on hypothalamic prolactin receptor expressing neurones in the mouse. Journal of Neuroendocrinology (2020) 32(11): e12908. [bioRxiv]

Gingell, J. J., Rees, T. A., Hendrikse, E. R., Siow, A., Rennison, D., Scotter, J., Harris, P. W. R., Brimble, M. A., Walker, C. S., & Hay, D. L.  Distinct Patterns of Internalization of Different Calcitonin Gene-Related Peptide Receptors. ACS Pharmacology and Translational Science (2020) 3(2): 296-304. [pdf]

Grant, P. S., Furkert, D. P., & Brimble, M. A.  Total Synthesis of (±)-Leonuketal. Organic Letters (2020) 22: 8735-8740. [chemRxiv]

Grattan, D. R., & Ladyman, S. R.  Neurophysiological and cognitive changes in pregnancy. Handbook of Clinical Neurology (2020) 171: 25-55.

Guise, C. P., Abbattista, M. R., Anderson, R. F., Li, D., Taghipouran, R., Tsai, A., Lee, S. J., Smaill, J. B., Denny, W. A., Hay, M. P., Wilson, W. R., Hicks, K. O., & Patterson, A. V.  Subcellular Location of Tirapazamine Reduction Dramatically Affects Aerobic but Not Anoxic Cytotoxicity. Molecules (Basel, Switzerland) (2020) 25(21): 4888.

Gustafson, P., Ladyman, S. R., McFadden, S., Larsen, C., Khant Aung, Z., Brown, R. S. E., Bunn, S. J., & Grattan, D. R.  Prolactin receptor-mediated activation of pSTAT5 in the pregnant mouse brain. Journal of Neuroendocrinology (2020) 32(11): e12901. 

Hards, K., Adolph, C., Harold, L. K., McNeil, M. B., Cheung, C. Y., Jinich, A., Rhee, K. Y., & Cook, G. M.  Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents. Progress in Biophysics and Molecular Biology (2020) 152: 35-44. 

Hendrikse, E. R., Liew, L. P., Bower, R. L., Bonnet, M., Jamaluddin, M. A., Prodan, N., Richards, K. D., Walker, C. S., Pairaudeau, G., Smith, D. M., Rujan, R. M., Sudra, R., Reynolds, C. A., Booe, J. M., Pioszak, A. A., Flanagan, J. U., Hay, M. P., & Hay, D. L.  Identification of Small-Molecule Positive Modulators of Calcitonin-like Receptor-Based Receptors. ACS Pharmacology and Translational Science (2020) 3(2): 305-320. 

Hermant, Y. O., Cameron, A. J., Harris, P. W. R., & Brimble, M. A.  Synthesis of antimicrobial lipopeptides using the “CLipPA” thiol-ene reaction. Methods in Molecular Biology (2020) 2103: 263-274. 

Hollywood, J. A., Przepiorski, A., D'Souza, R. F., Sreebhavan, S., Wolvetang, E. J., Harrison, P. T., Davidson, A. J., & Holm, T. M.  Use of human induced pluripotent stem cells and kidney organoids to develop a cysteamine/mtor inhibition combination therapy for cystinosis. Journal of the American Society of Nephrology (2020) 31(5): 962-982.

Jiao, W., Fan, Y., Blackmore, N. J., & Parker, E. J.  A single amino acid substitution uncouples catalysis and allostery in an essential biosynthetic enzyme in Mycobacterium tuberculosis. Journal of Biological Chemistry (2020) 295(19): 6252-6262. 

Jiao, W., Lang, E. J., Bai, Y., Fan, Y., & Parker, E. J.  Diverse allosteric componentry and mechanisms control entry into aromatic metabolite biosynthesis. Current Opinion in Structural Biology (2020) 65: 159-167. 

Kavianinia, I., Stubbing, L. A., Abbattista, M. R., Harris, P. W. R., Smaill, J. B., Patterson, A. V., & Brimble, M. A.  Alanine scan-guided synthesis and biological evaluation of analogues of culicinin D, a potent anticancer peptaibol. Bioorganic and Medicinal Chemistry Letters (2020) 30(11): 127135. 

Keown, J. R., Yang, J., Black, M. M., & Goldstone, D. C.  The RING domain of TRIM69 promotes higher-order assembly. Acta Crystallographica Section D: Structural Biology (2020) 76: 954-961. 

Ketharnathan, S., Labudina, A., & Horsfield, J. A.  Cohesin Components Stag1 and Stag2 Differentially Influence Haematopoietic Mesoderm Development in Zebrafish Embryos. Frontiers in Cell and Developmental Biology (2020) 8: 617545. 

Khant Aung, Z., Grattan, D. R., & Ladyman, S. R.  Pregnancy-induced adaptation of central sensitivity to leptin and insulin. Molecular and Cellular Endocrinology (2020) 516: 110933.

Khemlani, A. H. J., Proft, T., & Loh, J. M. S.  Assays to Analyze Adhesion of Group A Streptococcus to Host Cells. Methods in Molecular Biology (2020) 2136: 271-278.

Khemlani, A. H. J., Proft, T., & Loh, J. M. S.  A Mouse Nasopharyngeal Colonization Model for Group A Streptococcus. Methods in Molecular Biology (2020) 2136: 303-308.

Kokay, I. C., Grattan, D. R., & Murray, J. F.  Prolactin maintains transient melanin-concentrating hormone expression in the medial preoptic area during established lactation. Journal of Neuroendocrinology (2020) 32(2): e12827. 

Kvach, M. V., Barzak, F. M., Harjes, S., Schares, H. A. M., Kurup, H. M., Jones, K. F., Sutton, L., Donahue, J., D'Aquila, R. T., Jameson, G. B., Harki, D. A., Krause, K. L., Harjes, E., & Filichev, V. V.   Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2′-Deoxyzebularine Embedded in Single-Stranded DNA. ChemBioChem (2020) 21(7): 1028-1035. 

Ladyman, S. R., Hackwell, E. C. R., & Brown, R. S. E.  The role of prolactin in co-ordinating fertility and metabolic adaptations during reproduction. Neuropharmacology (2020) 167: 107911.

Lasham, A., Tsai, P., Fitzgerald, S. J., Mehta, S. Y., Knowlton, N. S., Braithwaite, A. W., & Print, C. G.  Accessing a New Dimension in TP53 Biology: Multiplex Long Amplicon Digital PCR to Specifically Detect and Quantitate Individual TP53 Transcripts. Cancers (Basel) (2020) 12(3): 769.

Le Tissier, P. R., & Grattan, D. R.  Growth hormone and prolactin: So much still to learn. Journal of Neuroendocrinology (2020) 32(11): e12909.

Lee, T. W., Yong, H., Bhatta, S., Singleton, D., Lipert, B., Tsai, P., Bohlander, S., Print, C., Hunter, F., Wilson, W., & Jamieson, S.  Functional genomics screens to identify genes involved in tolerance of tumour microenvironment stress. European Journal of Cancer (2020) 138: S30. 

Li, F. F., Stubbing, L. A., Kavianinia, I., Abbattista, M. R., Harris, P. W. R., Smaill, J. B., Patterson, A. V., & Brimble, M. A.  Synthesis and antiproliferative activity of C- and N-terminal analogues of culicinin D. Bioorganic and Medicinal Chemistry Letters (2020) 30(16): 127331

Loef, E. J., Brooks, A. E. S., Lorenz, N., Birch, N. P., & Dunbar, P. R.  Neuroserpin regulates human T cell-T cell interactions and proliferation through inhibition of tissue plasminogen activator. Journal of Leukocyte Biology (2020) 107(1): 145-158.

Loh, J. M. S., Soh, K. Y., & Proft, T.  Generation of Bioluminescent Group A Streptococcus for Biophotonic Imaging. Methods in Molecular Biology (2020) 2136: 71-77.

Lopez-Vicchi, F., De Winne, C., Brie, B., Sorianello, E., Ladyman, S. R., & Becu-Villalobos, D.  Metabolic functions of prolactin: Physiological and pathological aspects. Journal of Neuroendocrinology (2020) 32(11): e12888.

Lopez-Vicchi, F., Ladyman, S. R., Ornstein, A. M., Gustafson, P., Knowles, P., Luque, G. M., Grattan, D. R., & Becu-Villalobos, D.   Chronic high prolactin levels impact on gene expression at discrete hypothalamic nuclei involved in food intake. FASEB Journal (2020) 34(3): 3902-3914. 

Lu, B. L., Loomes, K. M., Hay, D. L., Harris, P. W. R., & Brimble, M. A.  Synthesis of isotopically labelled αCGRP8-37 and its lipidated analogue. Journal of Labelled Compounds and Radiopharmaceuticals (2020) 63(7): 325-332. [pdf]

Lu, B. L., Williams, G. M., & Brimble, M. A.  TLR2 agonists and their structure-activity relationships. Organic and Biomolecular Chemistry (2020) 18(27): 5073-5094. 

Lu, B. L., Williams, G. M., Verdon, D. J., Dunbar, P. R., & Brimble, M. A.  Synthesis and Evaluation of Novel TLR2 Agonists as Potential Adjuvants for Cancer Vaccines. Journal of Medicinal Chemistry (2020) 63(5): 2282-2291. [pdf]

Masson, S. W. C., Sorrenson, B., Shepherd, P. R., & Merry, T. L. (2020). β-catenin regulates muscle glucose transport via actin remodelling and M-cadherin binding. Molecular Metabolism (2020) 42, 101091.

McCone, J. A. J., Somarathne, K. K., Orme, C. L., Hewitt, R. J., Grant, E. R., Hall, K. R., Ackerley, D. F., La Flamme, A. C., & Harvey, J. E.  Total Synthesis and Bioactivity Studies of Fungal Metabolite (-)-TAN-2483B. Organic Letters (2020) 22(24): 9427-9432. 

McNeil, M. B., Ryburn, H. W. K., Harold, L. K., Tirados, J. F., & Cook, G. M.  Transcriptional Inhibition of the F(1)F(0)-Type ATP Synthase Has Bactericidal Consequences on the Viability of Mycobacteria. Antimicrobial Agents and Chemotherapy (2020) 64(8): e00492-20.

Mehta, S., Algie, M., Al-Jabry, T., McKinney, C., Kannan, S., Verma, C. S., Ma, W., Zhang, J., Bartolec, T. K., Masamsetti, V. P., Parker, K., Henderson, L., Gould, M. L., Bhatia, P., Harfoot, R., Chircop, M., Kleffmann, T., Cohen, S. B., Woolley, A. G., Cesare, A. J., & Braithwaite, A.  Critical role for cold shock protein YB-1 in cytokinesis. Cancers (2020) 12(9): 1-29.

Mehta, S., McKinney, C., Algie, M., Verma, C. S., Kannan, S., Harfoot, R., Bartolec, T. K., Bhatia, P., Fisher, A. J., Gould, M. L., Parker, K., Cesare, A. J., Cunliffe, H. E., Cohen, S. B., Kleffmann, T., Braithwaite, A. W., & Woolley, A. G.  Dephosphorylation of YB-1 is Required for Nuclear Localisation During G(2) Phase of the Cell Cycle. Cancers (Basel) (2020) 12(2): 315.

Merry, T. L., Brooks, A. E. S., Masson, S. W., Adams, S. E., Jaiswal, J. K., Jamieson, S. M. F., & Shepherd, P. R.  The CSF1 receptor inhibitor pexidartinib (PLX3397) reduces tissue macrophage levels without affecting glucose homeostasis in mice. International Journal of Obesity (London) (2020) 44(1): 245-253. 

Metcalfe, L. K., Krishnan, M., Turner, N., Yaghootkar, H., Merry, T. L., Dewes, O., Hindmarsh, J. H., De Zoysa, J., Dalbeth, N., Stamp, L. K., Merriman, T. R., Smith, G., Shepherd, P., & Murphy, R.  The Māori and Pacific specific CREBRF variant and adult height. International Journal of Obesity (2020) 44(3): 748-752. 

Mowday, A. M., Copp, J. N., Syddall, S. P., Dubois, L. J., Wang, J., Lieuwes, N. G., Biemans, R., Ashoorzadeh, A., Abbattista, M. R., Williams, E. M., Guise, C. P., Lambin, P., Ackerley, D. F., Smaill, J. B., Theys, J., & Patterson, A. V.  E. coli nitroreductase NfsA is a reporter gene for non-invasive PET imaging in cancer gene therapy applications. Theranostics (2020) 10(23): 10548-10562.

Munoz-Erazo, L., Rhodes, J. L., Marion, V. C., & Kemp, R. A.  Tertiary lymphoid structures in cancer – considerations for patient prognosis. Cellular and Molecular Immunology (2020) 17(6): 570-575. 

Naismith, J. H., & Parker, E.  Editorial overview: Catalysis and regulation. Current Opinion in Structural Biology (2020) 65: iii-iv. 

Nakatani, Y., Shimaki, Y., Dutta, D., Muench, S. P., Ireton, K., Cook, G. M., & Jeuken, L. J. C.  Unprecedented Properties of Phenothiazines Unraveled by a NDH-2 Bioelectrochemical Assay Platform. Journal of the American Chemical Society (2020) 142(3): 1311-1320. 

Nizi, M. G., Desantis, J., Nakatani, Y., Massari, S., Mazzarella, M. A., Shetye, G., Sabatini, S., Barreca, M. L., Manfroni, G., Felicetti, T., Rushton-Green, R., Hards, K., Latacz, G., Satała, G., Bojarski, A. J., Cecchetti, V., Kolář, M. H., Handzlik, J., Cook, G. M., Franzblau, S. G., & Tabarrini, O.  Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors. European Journal of Medicinal Chemistry (2020) 201: 112420. [PDF]

Oh, J. K., Przepiorski, A., Chang, H. H., Dodd, R. C., Sander, V., Sorrenson, B., Shih, J. H., Hollywood, J. A., de Zoysa, J. R., Shepherd, P. R., Davidson, A. J., & Holm, T. M.  Derivation of induced pluripotent stem cell lines from New Zealand donors. Journal of the Royal Society of New Zealand (2020) 10.1080/03036758.2020.1830808. [pdf]

Paterson, D. L., Flanagan, J. U., Shepherd, P. R., Harris, P. W. R., & Brimble, M. A.  Variable-Length Ester-Based Staples for α-Helical Peptides by Using A Double Thiol-ene Reaction. Chemistry - A European Journal (2020) 26(47): 10826-10833.

Phillipps, H. R., Yip, S. H., & Grattan, D. R.  Patterns of prolactin secretion. Molecular and Cellular Endocrinology (2020) 502: 110679.

Pioszak, A. A., & Hay, D. L.  RAMPs as allosteric modulators of the calcitonin and calcitonin-like class B G protein-coupled receptors. Advances in Pharmacology (2020) 88: 115-141.

Prentice, E. J., Hicks, J., Ballerstedt, H., Blank, L. M., Liang, L. L., Schipper, L. A., & Arcus, V. L.  The inflection point hypothesis: The relationship between the temperature dependence of enzyme-catalyzed reaction rates and microbial growth rates. Biochemistry (2020) 59(38): 3562-3569. [pdf]

Raynes, J. M., Tay, M. L., By, S. H., Steemson, J. D., & Moreland, N. J.  Isolation of Monoclonal Antibodies to Group A Streptococcus Antigens Using Phage Display. Methods in Molecular Biology (2020) 2136: 255-268. 

Roach, R. J., Garavís, M., González, C., Jameson, G. B., Filichev, V. V., & Hale, T. K.  Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes. Nucleic Acids Research (2020) 48(2): 682-693.

Routh, E. D., Pullikuth, A. K., Jin, G., Chifman, J., Chou, J. W., D'Agostino, R. B., Seino, K. I., Wada, H., Print, C. G., Zhang, W., Lu, Y., & Miller, L. D.  Transcriptomic Features of T Cell-Barren Tumors Are Conserved Across Diverse Tumor Types. Frontiers in Immunology (2020) 11: 57.

Shao, M., McNeil, M., Cook, G. M., & Lu, X.  MmpL3 inhibitors as antituberculosis drugs. European Journal of Medicinal Chemistry (2020) 200: 112390. 

Stagkourakis, S., Smiley, K. O., Williams, P., Kakadellis, S., Ziegler, K., Bakker, J., Brown, R. S. E., Harkany, T., Grattan, D. R., & Broberger, C.  A Neuro-hormonal Circuit for Paternal Behavior Controlled by a Hypothalamic Network Oscillation. Cell (2020) 182(4): 960-975. 

Tong, J. T. W., Kavianinia, I., Ferguson, S. A., Cook, G. M., Harris, P. W. R., & Brimble, M. A.  Synthesis of paenipeptin C′ analogues employing solution-phase CLipPA chemistry. Organic and Biomolecular Chemistry (2020) 18(23): 4381-4385. 

Tong, K. K. H., Hanif, M., Lovett, J. H., Hummitzsch, K., Harris, H. H., Söhnel, T., Jamieson, S. M. F., & Hartinger, C. G.  Thiourea-derived chelating ligands and their organometallic compounds: Investigations into their anticancer activity. Molecules (2020) 25(16): 3661.

Wang, Q., Gavin, W., Masiello, N., Tran, K. B., Laible, G., & Shepherd, P. R.  Cetuximab produced from a goat mammary gland expression system is equally efficacious as innovator cetuximab in animal cancer models. Biotechnology Reports (2020) 28: e00533. 

Wang, Y., Yang, S. H., Brimble, M. A., & Harris, P. W. R.  Recent Progress in the Synthesis of Homogeneous Erythropoietin (EPO) Glycoforms. ChemBioChem (2020) 21(23): 3301-3312. 

Whitcombe, A. L., Hanson-Manful, P., Jack, S., Upton, A., Carr, P. A., Williamson, D. A., Baker, M. G., Proft, T., &  Moreland, N. J.  Development and evaluation of a new triplex immunoassay that detects group a streptococcus antibodies for the diagnosis of rheumatic fever. Journal of Clinical Microbiology (2020) 58(9): e00300-20.

Yang, S. H., Clemett, C. A., Brimble, M. A., O'Carroll, S. J., & Harris, P. W. R.  Synthesis and biological evaluation of: S -lipidated lipopeptides of a connexin 43 channel inhibitory peptide. RSC Medicinal Chemistry (2020) 11(9): 1041-1047. 

Yang, S. H., Hermant, Y. O. J., Harris, P. W. R., & Brimble, M. A.  Replacement of the Acrid tert-Butylthiol and an Improved Isolation Protocol for Cysteine Lipidation on a Peptide or Amino Acid (CLipPA). European Journal of Organic Chemistry (2020) 2020(8): 944-947.

Yim, V., Kavianinia, I., Knottenbelt, M. K., Ferguson, S. A., Cook, G. M., Swift, S., Chakraborty, A., Allison, J. R., Cameron, A. J., Harris, P. W. R., &  Brimble, M. A.  “CLipP”ing on lipids to generate antibacterial lipopeptides. Chemical Science (2020) 11(22): 5759-5765. 

Yim, V. V., Cameron, A. J., Kavianinia, I., Harris, P. W. R., & Brimble, M. A.  Thiol-ene Enabled Chemical Synthesis of Truncated S-Lipidated Teixobactin Analogs. Frontiers in Chemistry (2020) 8(568): 568.

Yim, V. V., Kavianinia, I., Cameron, A. J., Harris, P. W. R., & Brimble, M. A.  Direct synthesis of cyclic lipopeptides using intramolecular native chemical ligation and thiol-ene CLipPA chemistry. Organic and Biomolecular Chemistry (2020) 18(15): 2838-2844. 

Young, P. G., & Baker, E. N.  Engineering of Group A Streptococcus Isopeptide Bonds into Immunoglobulin-Like Protein Domains. Methods in Molecular Biology (2020) 2136: 377-395.

Young, P. G., & Squire, C. J.  Molecular Superglues: Discovery and Engineering Orthogonalization. Methods in Molecular Biology (2020) 2073: 85-99.