Every year Maurice Wilkins Centre investigators produce a large number of peer-reviewed scientific papers and reviews published in international journals. Research directly supported by the Maurice Wilkins Centre generated the following scientific papers.
Aoki, M., P. Wartenberg, R. Grünewald, H.R. Phillipps, A. Wyatt, D.R. Grattan, and U. Boehm, Widespread cell-specific prolactin receptor expression in multiple murine organs. Endocrinology (2019) 160(11): 2587-2599.
Aquino, N.S.S., I.C. Kokay, C.T. Perez, S.R. Ladyman, P.C. Henriques, J.F. Silva, C. Broberger, D.R. Grattan, and R.E. Szawka, Kisspeptin stimulation of prolactin secretion requires kiss1 receptor but not in tuberoinfundibular dopaminergic neurons. Endocrinology (2019) 160(3): 522-533.
Augustine, R.A., P.J. Knowles, Z. Khant Aung, D.R. Grattan, and S.R. Ladyman, Impaired hypothalamic leptin sensitivity in pseudopregnant rats treated with chronic prolactin to mimic pregnancy. Journal of Neuroendocrinology (2019) 31(9): e12702.
Aung, H.L., T.J. Devine, C.V. Mulholland, V.L. Arcus, and G.M. Cook, Tackling tuberculosis in the indigenous people of New Zealand. The Lancet Public Health (2019) 4(10): e496.
Billington, E.O., R. Murphy, G.D. Gamble, K. Callon, N. Davies, L.D. Plank, M. Booth, and I.R. Reid, Fibroblast growth factor 23 levels decline following sleeve gastrectomy. Clinical Endocrinology (2019) 91(1): 87-93.
Blaser, A., H.S. Sutherland, A.S.T. Tong, P.J. Choi, D. Conole, S.G. Franzblau, C.B. Cooper, A.M. Upton, M. Lotlikar, W.A. Denny, and B.D. Palmer, Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline. Bioorganic and Medicinal Chemistry (2019) 27(7): 1283-1291.
Bridges, R.S. and D.R. Grattan, 30 years after: CNS actions of prolactin: Sources, mechanisms and physiological significance. Journal of Neuroendocrinology (2019) 31(3): e12669.
Brimble, M.A., Organic synthesis: Where to from now? A personal perspective from down under. Organic Letters (2019) 21(15): 5773-5774.
Brown, R.S.E., Z. Khant Aung, H.R. Phillipps, Z. Barad, H.J. Lein, U. Boehm, R.E. Szawka, and D.R. Grattan, Acute suppression of LH secretion by prolactin in female mice is mediated by kisspeptin neurons in the arcuate nucleus. Endocrinology (2019) 160(5): 1323-1332.
Buckley, B.J., H. Majed, A. Aboelela, E. Minaei, L. Jiang, K. Fildes, C.Y. Cheung, D. Johnson, D. Bachovchin, G.M. Cook, M. Huang, M. Ranson, and M.J. Kelso, 6-Substituted amiloride derivatives as inhibitors of the urokinase-type plasminogen activator for use in metastatic disease. Bioorganic and Medicinal Chemistry Letters (2019) 29(24).
Cameron, A.J., C.J. Squire, A. Gérenton, L.A. Stubbing, P.W.R. Harris, and M.A. Brimble, Investigations of the key macrolactamisation step in the synthesis of cyclic tetrapeptide pseudoxylallemycin A. Organic and Biomolecular Chemistry (2019) 17(16): 3902-3913.
Chen, Y., J. Lu, R. Nemati, L.D. Plank, and R. Murphy, Acute changes of bile acids and FGF19 after sleeve gastrectomy and Roux-en-Y gastric bypass. Obesity Surgery (2019) 29(11): 3605-3621.
Choi, P.J., E. Cooper, P. Schweder, E. Mee, R. Faull, W.A. Denny, M. Dragunow, T.I.H. Park, and J. Jose, The synthesis of a novel Crizotinib heptamethine cyanine dye conjugate that potentiates the cytostatic and cytotoxic effects of Crizotinib in patient-derived glioblastoma cell lines. Bioorganic and Medicinal Chemistry Letters (2019) 29(18): 2617-2621.
Compton, B.J., K.J. Farrand, C.W. Tang, T.L. Osmond, M. Speir, A. Authier-Hall, J. Wang, P.M. Ferguson, S.T.S. Chan, R.J. Anderson, T.R. Cooney, C.M. Hayman, G.M. Williams, M.A. Brimble, C.R. Brooks, L.K. Yong, L.S. Metelitsa, D.M. Zajonc, D.I. Godfrey, O. Gasser, R. Weinkove, G.F. Painter, and I.F. Hermans, Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist. Organic and Biomolecular Chemistry (2019) 17(5): 1225-1237.
Cordero, P.R.F., R. Grinter, K. Hards, M.J. Cryle, C.G. Warr, G.M. Cook, and C. Greening, Two uptake hydrogenases differentially interact with the aerobic respiratory chain during mycobacterial growth and persistence. Journal of Biological Chemistry (2019) 294(50): 18980-18991.
Daniels, B.J., F.F. Li, D.P. Furkert, and M.A. Brimble, Naturally Occurring Lumazines. Journal of Natural Products (2019) 82(7): 2054-2065.
Darnell, R.L., M.K. Knottenbelt, F.O.T. Rose, I.R. Monk, T.P. Stinear, and G.M. Cook, Genomewide profiling of the Enterococcus faecalis transcriptional response to teixobactin reveals CroRS as an essential regulator of antimicrobial tolerance. mSphere (2019) 4(3).
Darnell, R.L., Y. Nakatani, M.K. Knottenbelt, S. Gebhard, and G.M. Cook, Functional characterization of bcrr: A one-component transmembrane signal transduction system for bacitracin resistance. Microbiology (United Kingdom) (2019) 165(4): 475-487.
Davies, N.K., J.M. O'Sullivan, L.D. Plank, and R. Murphy, Altered gut microbiome after bariatric surgery and its association with metabolic benefits: A systematic review. Surgery for Obesity and Related Diseases (2019) 15(4): 656-665.
Davison, E.K. and M.A. Brimble, Natural product derived privileged scaffolds in drug discovery. Current Opinion in Chemical Biology (2019) 52: 1-8.
Davison, E.K., A.J. Cameron, P.W.R. Harris, and M.A. Brimble, Synthesis of endolides A and B: Naturally occurring N-methylated cyclic tetrapeptides. MedChemComm (2019) 10(5): 693-698.
Dimitrov, I.V., M.G. Harvey, L.J. Voss, J.W. Sleigh, M.J. Bickerdike, and W.A. Denny, Ketamine esters and amides as short-acting anaesthetics: Structure-activity relationships for the side-chain. Bioorganic and Medicinal Chemistry (2019) 27(7): 1226-1231.
Ding, X.B., D.P. Furkert, and M.A. Brimble, Highly diastereoselective synthesis of syn-1,3-dihydroxyketone motifs from propargylic alcohols via spiroepoxide intermediates. Angewandte Chemie - International Edition (2019) 58(34): 11830-11835.
Dobson, R., R. Whittaker, Y. Jiang, C. McNamara, M. Shepherd, R. Maddison, R. Cutfield, M. Khanolkar, and R. Murphy, Long-term follow-up of a randomized controlled trial of a text-message diabetes self-management support programme, SMS4BG. Diabetic Medicine (2019) 37(2): 311-318.
Field, J.J., A.J. Singh, S. Sinha, M.R. Rowe, W.A. Denny, D.G. Brooke, and J.H. Miller, Synthesis and microtubule-destabilizing activity of N-Cyclopropyl-4-((3,4-dihydroquinolin-1(2H)-yl)sulfonyl)benzamide and its analogs. Chemistry - An Asian Journal (2019) 14(8): 1151-1157.
Freeman, J.L., M.A. Brimble, and D.P. Furkert, A chiral auxiliary-based synthesis of the C5-C17: Trans -decalin framework of anthracimycin. Organic Chemistry Frontiers (2019) 6(16): 2954-2963.
Freeman, J.L., M.A. Brimble, and D.P. Furkert, Convenient access to 5-membered cyclic iminium ions: Evidence for a stepwise [4 + 2] cycloaddition mechanism. Organic and Biomolecular Chemistry (2019) 17(10): 2705-2714.
Gamage, S.A., J.A. Spicer, K.Y. Tsang, P.D. O'Connor, J.U. Flanagan, W.J. Lee, J.M.J. Dickson, P.R. Shepherd, W.A. Denny, and G.W. Rewcastle, Synthesis and evaluation of imidazo[1,2-a]pyridine analogues of the ZSTK474 class of phosphatidylinositol 3-kinase inhibitors. Chemistry - An Asian Journal (2019) 14(8): 1249-1261.
Gane, E., D.J. Verdon, A.E. Brooks, A. Gaggar, A.H. Nguyen, G.M. Subramanian, C. Schwabe, and P.R. Dunbar, Anti-PD-1 blockade with nivolumab with and without therapeutic vaccination for virally suppressed chronic hepatitis B: A pilot study. Journal of Hepatology (2019) 71(5): 900-907.
Giddens, A.C., S.A. Gamage, J.D. Kendall, W.J. Lee, B.C. Baguley, C.M. Buchanan, S.M.F. Jamieson, J.M.J. Dickson, P.R. Shepherd, W.A. Denny, and G.W. Rewcastle, Synthesis and biological evaluation of solubilized sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474. Bioorganic and Medicinal Chemistry (2019) 27(8): 1529-1545.
Gillard, R.M. and M.A. Brimble, Benzannulated spiroketal natural products: Isolation, biological activity, biosynthesis, and total synthesis. Organic and Biomolecular Chemistry (2019) 17(36): 8272-8307.
Grant, P.S., M.A. Brimble, and D.P. Furkert, Synthesis of the bicyclic lactone core of leonuketal, enabled by a telescoped Diels-Alder reaction sequence. Chemistry - An Asian Journal (2019) 14(8): 1128-1135.
Grant, P.S., N. Kahlcke, K. Govindpani, M. Hunter, C. MacDonald, M.A. Brimble, M. Glass, and D.P. Furkert, Divalent cannabinoid-1 receptor ligands: A linker attachment point survey of SR141716A for development of high-affinity CB1R molecular probes. Bioorganic and Medicinal Chemistry Letters (2019) 29(21): 126644.
Grattan, D.R. and R.E. Szawka, Kisspeptin and prolactin. Seminars in Reproductive Medicine (2019) 37(2): 93-104.
Hards, K., S.M. Rodriguez, C. Cairns, and G.M. Cook, Alternate quinone coupling in a new class of succinate dehydrogenase may potentiate mycobacterial respiratory control. FEBS Letters (2019) 593(5): 475-486.
Harold, L.K., J. Antoney, F.H. Ahmed, K. Hards, P.D. Carr, T. Rapson, C. Greening, C.J. Jackson, and G.M. Cook, FAD-sequestering proteins protect mycobacteria against hypoxic and oxidative stress. Journal of Biological Chemistry (2019) 294(8): 2903-2912.
Harvey, M., J. Sleigh, L. Voss, M. Bickerdike, I. Dimitrov, and W. Denny, KEA-1010, a ketamine ester analogue, retains analgesic and sedative potency but is devoid of Psychomimetic effects. BMC Pharmacology and Toxicology (2019) 20(1): 85.
Hasenoehrl, E.J., D. Rae Sajorda, L. Berney-Meyer, S. Johnson, J.A.M. Tufariello, T. Fuhrer, G.M. Cook, W.R. Jacobs, and M. Berney, Derailing the aspartate pathway of Mycobacterium tuberculosis to eradicate persistent infection. Nature Communications (2019) 10(1): 4215.
Heitz, S.D., D.J. Hamelin, R.M. Hoffmann, N. Greenberg, G. Salloum, Z. Erami, B.D. Khalil, A. Shymanets, E.A. Steidle, G.Q. Gong, B. Nürnberg, J.E. Burke, J.U. Flanagan, A.R. Bresnick, and J.M. Backer, A single discrete Rab5-binding site in phosphoinositide 3-kinase is required for tumor cell invasion. Journal of Biological Chemistry (2019) 294(12): 4621-4633.
Jacobson, G.M., L.J. Voss, A. Klockars, S. Bird, I. Dimitrov, W.A. Denny, P.K. Olszewski, J.W. Sleigh, and M.G. Harvey, Transcriptional changes in response to ketamine ester-analogs SN 35210 and SN 35563 in the rat brain. BMC Genomics (2019) 20(1): 281.
Jeong, J.Y., J. Sperry, and M.A. Brimble, Synthesis of the tetracyclic cores of the integrastatins, epicoccolide A and epicocconigrone A. Journal of Organic Chemistry (2019) 84(18): 11935-11944.
Kalyukina, M., Y. Yosaatmadja, M.J. Middleditch, A.V. Patterson, J.B. Smaill, and C.J. Squire, TAS-120 cancer target binding: Defining reactivity and revealing the first fibroblast growth factor receptor 1 (FGFR1) irreversible structure. ChemMedChem (2019) 14(4): 494-500.
Kasim, J.K., I. Kavianinia, P.W.R. Harris, and M.A. Brimble, Three decades of amyloid beta synthesis: Challenges and advances. Frontiers in Chemistry (2019) 7(JUL).
Kasim, J.K., I. Kavianinia, J. Ng, P.W.R. Harris, N.P. Birch, and M.A. Brimble, Efficient synthesis and characterisation of the amyloid beta peptide, Aβ <inf>1-42</inf> , using a double linker system. Organic and Biomolecular Chemistry (2019) 17(1): 30-34.
Kazantseva, M., S. Mehta, R.A. Eiholzer, G. Gimenez, S. Bowie, H. Campbell, A.L. Reily-Bell, I. Roth, S. Ray, C.J. Drummond, G. Reid, S.M. Joruiz, A. Wiles, H.R. Morrin, K.L. Reader, N.A. Hung, M.A. Baird, T.L. Slatter, and A.W. Braithwaite, The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer. Cell Death and Disease (2019) 10(9): 631.
Kelch, I.D., G. Bogle, G.B. Sands, A.R.J. Phillips, I.J. LeGrice, and P.R. Dunbar, High-resolution 3D imaging and topological mapping of the lymph node conduit system. PLoS Biology (2019) 17(12): e3000486.
Khalil, Z.G., T.A. Hill, L.M. De Leon Rodriguez, R.J. Lohman, H.N. Hoang, N. Reiling, D. Hillemann, M.A. Brimble, D.P. Fairlie, A. Blumenthal, and R.J. Capon, Structure-activity relationships of wollamide cyclic hexapeptides with activity against drug-resistant and intracellular mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy (2019) 63(3).
Kirk, S.E., D.R. Grattan, and S.J. Bunn, The median eminence detects and responds to circulating prolactin in the male mouse. Journal of Neuroendocrinology (2019) 31(6): e12733.
Lee, D.J., A.J. Cameron, T.H. Wright, P.W.R. Harris, and M.A. Brimble, A synthetic approach to 'click' neoglycoprotein analogues of EPO employing one-pot native chemical ligation and CuAAC chemistry. Chemical Science (2019) 10(3): 815-828.
Lee, K.L., J.F. Aitken, H.L. Hsu, G.M. Williams, M.A. Brimble, and G.J.S. Cooper, Glucoregulatory activity of vesiculin in insulin sensitive and resistant mice. Peptides (2019) 116: 1-7.
Lee, W.G., C.I. Wells, J.L. McCall, R. Murphy, and L.D. Plank, Prevalence of diabetes in liver cirrhosis: A systematic review and meta-analysis. Diabetes/Metabolism Research and Reviews (2019) 35(6).
Li, F.F. and M.A. Brimble, Using chemical synthesis to optimise antimicrobial peptides in the fight against antimicrobial resistance. Pure and Applied Chemistry (2019) 91(2): 181-198.
Liew, L.P., Singleton, D.C., Wong, W.W., Cheng, G.J., Jamieson, S.M. and Hay, M.P. Hypoxia‐activated prodrugs of PERK inhibitors. Chemistry - An Asian Journal (2019) 14(8): 1238-1248.
Lu, B.L., G.M. Williams, D.J. Verdon, P.R. Dunbar, and M.A. Brimble, Synthesis and evaluation of novel TLR2 agonists as potential adjuvants for cancer vaccines. Journal of Medicinal Chemistry (2019) 63(5):2282-2291.
Lu, X., H. Chen, A. V. Patterson, J. B. Smaill, and K. Ding, Fibroblast growth factor receptor 4 (FGFR4) selective inhibitors as hepatocellular carcinoma therapy: Advances and prospects. Journal of Medicinal Chemistry (2019) 62(6): 2905-2915.
Lu, X., Z. Williams, K. Hards, J. Tang, C.Y. Cheung, H.L. Aung, B. Wang, Z. Liu, X. Hu, A. Lenaerts, L. Woolhiser, C. Hastings, X. Zhang, Z. Wang, K. Rhee, K. Ding, T. Zhang, and G.M. Cook, Pyrazolo[1,5- a]pyridine inhibitor of the respiratory cytochrome bcc complex for the treatment of drug-resistant tuberculosis. ACS Infectious Diseases (2019) 5(2): 239-249.
McNeil, M.B. and G.M. Cook, Utilization of CRISPR interference to validate MmpL3 as a drug target in mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy (2019) 63(8).
Metcalfe, L.K., M. Krishnan, N. Turner, H. Yaghootkar, T.L. Merry, O. Dewes, J.H. Hindmarsh, J. De Zoysa, N. Dalbeth, L.K. Stamp, T.R. Merriman, G. Smith, P. Shepherd, and R. Murphy, The Māori and Pacific specific CREBRF variant and adult height. International Journal of Obesity (2019) 44(3): 748-752.
Momin, M.A.M., B. Rangnekar, S. Sinha, C.Y. Cheung, G.M. Cook, and S.C. Das, Inhalable dry powder of bedaquiline for pulmonary tuberculosis: In vitro physicochemical characterization, antimicrobial activity and safety studies. Pharmaceutics (2019) 11(10).
Mulholland, C.V., A.C. Shockey, H.L. Aung, R.T. Cursons, R.F. O’Toole, S.S. Gautam, D. Brites, S. Gagneux, S.A. Roberts, N. Karalus, G.M. Cook, C.S. Pepperell, and V.L. Arcus, Dispersal of mycobacterium tuberculosis driven by historical European trade in the South Pacific. Frontiers in Microbiology (2019) 10: 2778.
Murphy, R., G.D. Gamble, M. House, B. Pool, A. Horne, T.R. Merriman, and N. Dalbeth, Greater insulin response to acute fructose ingestion among Māori and Pacific people compared to European people living in Aotearoa New Zealand. Internal Medicine Journal (2019) 49(2): 196-202.
Murphy, R., M. Ghafel, G. Beban, M. Booth, K. Bartholomew, and P. Sandiford, Variation in public-funded bariatric surgery intervention rate by New Zealand region. Internal Medicine Journal (2019) 49(3): 391-395.
Murphy, R., X.C. Morgan, X.Y. Wang, K. Wickens, G. Purdie, P. Fitzharris, A. Otal, B. Lawley, T. Stanley, C. Barthow, J. Crane, E.A. Mitchell, and G.W. Tannock, Eczema-protective probiotic alters infant gut microbiome functional capacity but not composition: Sub-sample analysis from a RCT. Beneficial Microbes (2019) 10(1): 5-17.
Musa, H., E.R. Hendrikse, M.A. Brimble, M.L. Garelja, H.A. Watkins, P.W.R. Harris, and D.L. Hay, Pharmacological characterization and investigation of N-terminal loop amino acids of adrenomedullin 2 that are important for receptor activation. Biochemistry (2019) 58(32): 3468-3474.
Ng, J., H. Kaur, T. Collier, K. Chang, A.E.S. Brooks, J.R. Allison, M.A. Brimble, A. Hickey, and N.P. Birch, Site-specific glycation of A1- 42 affects fibril formation and is neurotoxic. Journal of Biological Chemistry (2019) 294(22): 8806-8818.
Okesene-Gafa, K.A.M., M. Li, C.J.D. McKinlay, R.S. Taylor, E.C. Rush, C.R. Wall, J. Wilson, R. Murphy, R. Taylor, J.M.D. Thompson, C.A. Crowther, and L.M.E. McCowan, Effect of antenatal dietary interventions in maternal obesity on pregnancy weight-gain and birthweight: Healthy Mums and Babies (HUMBA) randomized trial. American Journal of Obstetrics and Gynecology (2019) 221(2): 152.e1-152.e13.
Patil, M., S. Belugin, J. Mecklenburg, A. Wangzhou, C. Paige, P.A. Barba-Escobedo, J.T. Boyd, V. Goffin, D. Grattan, U. Boehm, G. Dussor, T.J. Price, and A.N. Akopian, Prolactin regulates pain responses via a female-selective nociceptor-specific mechanism. iScience (2019) 20: 449-465.
Patil, M., A.H. Hovhannisyan, A. Wangzhou, J. Mecklenburg, W. Koek, V. Goffin, D. Grattan, U. Boehm, G. Dussor, T.J. Price, and A.N. Akopian, Prolactin receptor expression in mouse dorsal root ganglia neuronal subtypes is sex-dependent. Journal of Neuroendocrinology (2019) 31(8): e12759.
Petri, J., Y. Nakatani, M.G. Montgomery, S.A. Ferguson, D. Aragão, A.G.W. Leslie, A. Heikal, J.E. Walker, and G.M. Cook, Structure of F1-ATPase from the obligate anaerobe Fusobacterium nucleatum. Open Biology (2019) 9(6): 190066.
Phillipps, H.R., C.J. Rand, R.S.E. Brown, I.C. Kokay, J.A. Stanton, and D.R. Grattan, Prolactin regulation of insulin-like growth factor 2 gene expression in the adult mouse choroid plexus. FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology (2019) 33(5): 6115-6128.
Pilkington, L.I., X. Yang, M.W. Liu, Y. Hemar, M.A. Brimble, and J. Reynisson, A chemometric analysis of compounds from native New Zealand medicinal flora. Chemistry - An Asian Journal (2019) 14(8): 1117-1127.
Ramke, J., V. Jordan, A.L. Vincent, M. Harwood, R. Murphy, and S. Ameratunga, Diabetic eye disease and screening attendance by ethnicity in New Zealand: A systematic review. Clinical and Experimental Ophthalmology (2019) 47(7): 937-947.
Rushton-Green, R., R.L. Darnell, G. Taiaroa, G.P. Carter, G.M. Cook, and X.C. Morgan, Agricultural origins of a highly persistent lineage of vancomycin-resistant Enterococcus faecalis in New Zealand. Applied and Environmental Microbiology (2019) 85(13).
Santoso, K.T., C.Y. Cheung, K. Hards, G.M. Cook, B.L. Stocker, and M.S.M. Timmer, Synthesis and investigation of Phthalazinones as antitubercular agents. Chemistry - An Asian Journal (2019) 14(8): 1278-1285.
Santoso, K.T., A. Menorca, C.Y. Cheung, G.M. Cook, B.L. Stocker, and M.S.M. Timmer, The synthesis and evaluation of quinolinequinones as anti-mycobacterial agents. Bioorganic and Medicinal Chemistry (2019) 27(16): 3532-3545.
Saponara, S., F. Fusi, O. Spiga, A. Trezza, B. Hopkins, M.A. Brimble, D. Rennison, and S. Bova, The selective rat toxicant norbormide blocks KATP channels in smooth muscle cells but not in insulin-secreting cells. Frontiers in Pharmacology (2019) 10(MAY).
Sarojini, V., A.J. Cameron, K.G. Varnava, W.A. Denny, and G. Sanjayan, Cyclic tetrapeptides from nature and design: A review of synthetic methodologies, structure, and function. Chemical Reviews (2019) 119(17): 10318-10359.
Saw, W.G., M.L. Wu, P. Ragunathan, G. Biuković, A.M. Lau, J. Shin, A. Harikishore, C.Y. Cheung, K. Hards, J.P. Sarathy, R.W. Bates, G.M. Cook, T. Dick, and G. Grüber, Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis. Scientific Reports (2019) 9(1): 16759.
Skinner, N.J., M.Z. Rizwan, D.R. Grattan, and A. Tups, Chronic light cycle disruption alters central insulin and leptin signaling as well as metabolic markers in male mice. Endocrinology (2019) 160(10): 2257-2270.
Slykerman, R.F., M.V. Joglekar, A.A. Hardikar, S.N. Satoor, J.M.D. Thompson, A. Jenkins, E.A. Mitchell, and R. Murphy, Maternal stress during pregnancy and small for gestational age birthweight are not associated with telomere length at 11 years of age. Gene (2019) 694: 97-101.
Smiley, K.O., S.R. Ladyman, P. Gustafson, D.R. Grattan, and R.S.E. Brown, Neuroendocrinology and adaptive physiology of maternal care. Current Topics in Behavioral Neurosciences (2019) 43: 161-210.
Smith, R.J., R.L. Bower, S.A. Ferguson, R.J. Rosengren, G.M. Cook, and B.C. Hawkins, The synthesis of (±)-oxyisocyclointegrin. European Journal of Organic Chemistry (2019) 2019(7): 1571-1573.
Spicer, J.A., C.K. Miller, P.D. O'Connor, J. Jose, A.C. Giddens, J.K. Jaiswal, S.M.F. Jamieson, M.R. Bull, W.A. Denny, H. Akhlaghi, J.A. Trapani, G.R. Hill, K. Chang, and K.H. Gartlan, Inhibition of the cytolytic protein perforin prevents rejection of transplanted bone marrow stem cells in vivo. Journal of Medicinal Chemistry (Epub 2019) DOI: 10.1021/acs.jmedchem.9b00881.
Stevenson, L.J., J.G. Owen, and D.F. Ackerley, Metagenome driven discovery of nonribosomal peptides. ACS Chemical Biology (2019) 14(10): 2115-2126.
Stubbing, L.A., I. Kavianinia, M.R. Abbattista, P.W.R. Harris, J.B. Smaill, A.V. Patterson, and M.A. Brimble, Synthesis and antiproliferative activity of culicinin D analogues containing simplified AHMOD-based residues. European Journal of Medicinal Chemistry (2019) 177: 235-246.
Sutherland, H.S., A.S.T. Tong, P.J. Choi, A. Blaser, D. Conole, S.G. Franzblau, M.U. Lotlikar, C.B. Cooper, A.M. Upton, W.A. Denny, and B.D. Palmer, 3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel. Bioorganic and Medicinal Chemistry (2019) 27(7): 1292-1307.
Svendsen, J.S.M., T.M. Grant, D. Rennison, M.A. Brimble, and J. Svenson, Very short and stable lactoferricin-derived antimicrobial peptides: Design principles and potential uses. Accounts of Chemical Research (2019) 52(3): 749-759.
Thompson, A.M. and W.A. Denny, Inhibitors of enzymes in the electron transport chain of Mycobacterium tuberculosis. in Annual Reports in Medicinal Chemistry (2019) 52: 97-130.
Trevarton, A., Y. Zhou, D. Yang, G.W. Rewcastle, J.U. Flanagan, A. Braithwaite, P.R. Shepherd, C.G. Print, M.W. Wang, and A. Lasham, Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1. Acta Pharmaceutica Sinica B (2019) 9(5): 997-1007.
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