The Maurice Wilkins Centre supports the development of new technologies, and applications of technologies, for medical research. This ensures scientists have the high-tech capability to deliver on their ideas, accelerating the discovery of new drugs, vaccines and diagnostic techniques.
Its technology programme feeds directly into its human disease research programmes – focused on cancer, diabetes and metabolic disease, and infectious disease – or has the capability to be used in this way in future.
In supporting inter-disciplinary research, the Centre also stimulates adaptation of technology from one scientific field to another, a process that often generates exciting new capabilities.
The Centre has particular strengths in computer-based technologies to integrate complex information about biological systems. Its other work ranges from developing new methods in synthetic chemistry to new forms of three-dimensional imaging.
THE MAURICE WILKINS CENTRE UNDERTAKES RESEARCH IN THE FOLLOWING AREAS
New modalities for challenging drug discovery
Advances in molecular biology have heralded an expansion of protein-based therapeutics, and sophisticated peptide chemistry has also opened up new therapeutic options.
Transition state analysis as a smart approach to the development of novel tailored therapeutics
Maurice Wilkins Centre scientists are using an approach called transition state analysis to generate potent and selective enzyme inhibitors, several of which have already been tested in preclinical and human trials for their potential as treatments for a variety of infectious diseases, haematological disorders and gout.
Early-stage target selection & drug screening
The Maurice Wilkins Centre has a history of success developing new drugs and vaccines for a variety of diseases. This programme aims to increase the efficiency of our processes for identifying and developing new agents.
Advanced cell & tissue culture technology
The Centre funds research to investigate how human tissue can be more efficiently grown for downstream purposes, including modelling human systems to better understand disease or replace damaged tissue.