How does bariatric surgery improve glucose homeostasis?
Surgical reduction of the size of the stomach and small intestine has proven to be one of the most successful ways of achieving long-term remissions in obesity and type-2 diabetes.
The Maurice Wilkins Centre has funded studies to support the evaluation of direct comparisons of the long-term efficacy of two types of such surgery, namely Roux-en-Y and sleeve gastrectomy, in New Zealand patients. Our studies will investigate how the surgery affects the gut microbiome, as it is becoming clear the composition of bacteria in our gut is a key modulator of whole body energy metabolism.
The research we are doing in this area will help to define the potential role of bariatric surgery in the range of options for treating obesity and type-2 diabetes in New Zealand.