Diabetes & Metabolic Disease
The rate of diabetes (type II) is increasing hand in hand with obesity and now poses a major health problem in most developed countries, including New Zealand. Diabetes accelerates many other disease processes, including cardiovascular disease, but the mechanisms linking the metabolic changes associated with obesity through to diabetes and cardiovascular disease are still far from clear.
The Maurice Wilkins Centre research programme in diabetes and related metabolic conditions aims to identify pathways to new treatments for diabetes and its associated complications.
THE MAURICE WILKINS CENTRE UNDERTAKES RESEARCH IN THE FOLLOWING AREAS
Hormones controlling metabolism
Human metabolic disorders are often associated with defects in the production or release of key metabolic hormones.
Genetic predisposition to obesity and diabetes in New Zealand populations
Rates of obesity and type-2 diabetes are 2-3 times higher in Māori and Pacific populations than for the general population in New Zealand. This therefore represents a major health challenge of particular importance to the country.
How does bariatric surgery improve glucose homeostasis?
Surgical reduction of the size of the stomach and small intestine has proven to be one of the most successful ways of achieving long-term remissions in obesity and type-2 diabetes.