Cancer is a major health concern to people around the world and a strong focus of the Maurice Wilkins Centre’s research.
Our investigators are carrying out research into how cancer cells function, identifying potential drug targets in the cancer cell, developing new anti-cancer drugs and looking at how the human body copes with some cancer drug treatments.
They have genuine “bench-to-bedside” capability, having led both the fundamental science developing new cancer drugs and diagnostics, and founding companies responsible for taking those discoveries into the clinic.
The MWC is currently supporting an Immuno-oncology flagship programme, which draws the expertise of researchers from across the cancer theme.
THE MAURICE WILKINS CENTRE UNDERTAKES RESEARCH IN THE FOLLOWING AREAS
Immune therapy is one of the most exciting and promising areas of clinical cancer research. At the Maurice Wilkins Centre, our investigators have discovered several immune modulating drugs and vaccines that have the potential to help the body's immune system fight cancer.
Molecular approaches to cancer therapy
Most cancers are associated with mutations in the signalling proteins found in cells. A better understanding of the signalling pathways underlying many cancers is aiding progress in the development of novel molecular-targeted drug therapies.
Banishing tumour hypoxia and relieving immunosuppression in cancer
Tumours are typically hypoxic – deprived of oxygen – producing microenvironments that greatly reduce the ability of traditional cancer immunotherapies to work properly. However, researchers are working towards overcoming this barrier.
Genomic approaches to cancer diagnosis and treatment
As cancer therapy increasingly involves immune approaches, genomic techniques are being applied to the analysis of immune responses to cancer as well as cancer cells themselves.